Subcutaneous antihistamine injection is effective to control a local allergic reaction to human insulin

Diabetes Res Clin Pract. 2009 Sep;85(3):e42-3. doi: 10.1016/j.diabres.2009.05.013. Epub 2009 Jun 10.

Abstract

A 31-year-old woman, having a type-1 diabetes and an insulin allergy, was successfully treated with a subcutaneous antihistamine injection to the next continuous subcutaneous insulin infusion site.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Diabetes Mellitus, Type 1 / drug therapy*
  • Diabetes Mellitus, Type 1 / immunology
  • Drug Hypersensitivity / drug therapy*
  • Drug Hypersensitivity / pathology
  • Female
  • Histamine Antagonists / administration & dosage
  • Histamine Antagonists / therapeutic use*
  • Humans
  • Injections, Subcutaneous
  • Insulin / adverse effects*
  • Pruritus / chemically induced
  • Pruritus / drug therapy
  • Pruritus / pathology
  • Recombinant Proteins / adverse effects*
  • Skin / drug effects
  • Skin / immunology
  • Skin / pathology

Substances

  • Histamine Antagonists
  • Insulin
  • Recombinant Proteins