Abstract
A Ru(bpy)(3)(2+) photosensitizer was covalently linked at specific sites on the interior or exterior surface of genetic constructs of a small heat shock protein cage nanoplatform and the light activated production of singlet oxygen was characterized.
MeSH terms
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2,2'-Dipyridyl / analogs & derivatives*
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2,2'-Dipyridyl / chemistry
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2,2'-Dipyridyl / metabolism
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Archaeal Proteins / chemistry
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Archaeal Proteins / genetics*
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Archaeal Proteins / metabolism*
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Coordination Complexes
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Heat-Shock Proteins / chemistry
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Heat-Shock Proteins / genetics*
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Heat-Shock Proteins / metabolism*
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Methanococcus / metabolism
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Models, Molecular
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Mutation*
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Photosensitizing Agents / chemistry
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Photosensitizing Agents / metabolism*
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Protein Conformation
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Reactive Oxygen Species / metabolism
Substances
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Archaeal Proteins
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Coordination Complexes
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Heat-Shock Proteins
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Photosensitizing Agents
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Reactive Oxygen Species
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tris(2,2-bipyridine)-ruthenium(II)
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2,2'-Dipyridyl