Disruption of transcriptionally active Stat3 dimers with non-phosphorylated, salicylic acid-based small molecules: potent in vitro and tumor cell activities

Chembiochem. 2009 Aug 17;10(12):1959-64. doi: 10.1002/cbic.200900172.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aminosalicylic Acids / chemical synthesis
  • Aminosalicylic Acids / chemistry
  • Aminosalicylic Acids / pharmacology
  • Benzenesulfonates / chemical synthesis
  • Benzenesulfonates / chemistry
  • Benzenesulfonates / pharmacology
  • Cell Proliferation / drug effects
  • Dimerization
  • Humans
  • Models, Molecular
  • Neoplasms / chemistry
  • Neoplasms / metabolism*
  • Neoplasms / pathology*
  • STAT3 Transcription Factor / antagonists & inhibitors*
  • STAT3 Transcription Factor / chemistry
  • STAT3 Transcription Factor / metabolism*
  • Salicylic Acid / chemical synthesis
  • Salicylic Acid / chemistry
  • Salicylic Acid / pharmacology*
  • Signal Transduction
  • Small Molecule Libraries

Substances

  • Aminosalicylic Acids
  • Benzenesulfonates
  • NSC 74859
  • STAT3 Transcription Factor
  • Small Molecule Libraries
  • Salicylic Acid