Kinetics of nasopharyngeal shedding of novel H1N1 (swine-like) influenza A virus in an immunocompetent adult under oseltamivir therapy

C Charlier; V Enouf; F Lanternier; M Grandadam; K Amazzough; S Blanche; M Lecuit; O Lortholary; S van der Werf

doi:10.1111/j.1469-0691.2009.03007.x

Kinetics of nasopharyngeal shedding of novel H1N1 (swine-like) influenza A virus in an immunocompetent adult under oseltamivir therapy

Clin Microbiol Infect. 2009 Dec;15(12):1189-91. doi: 10.1111/j.1469-0691.2009.03007.x. Epub 2009 Jul 22.

Authors

C Charlier¹, V Enouf, F Lanternier, M Grandadam, K Amazzough, S Blanche, M Lecuit, O Lortholary, S van der Werf

Affiliation

¹ Université Paris Descartes, Service de Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker-Pasteur, Hôpital Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Paris, France.

PMID: 19681951
DOI: 10.1111/j.1469-0691.2009.03007.x

Abstract

We describe a patient with confirmed novel H1N1 (swine-like) influenza A virus who had daily nasal swabs tested during oseltamivir therapy. Nasal shedding remained positive for 2 days and became negative on day 3. This report presents the first available data on the kinetics of shedding of this novel virus under antiviral therapy.

Publication types

Case Reports

MeSH terms

Adult
Animals
Antiviral Agents / therapeutic use*
Humans
Immunocompetence*
Influenza A Virus, H1N1 Subtype / drug effects
Influenza A Virus, H1N1 Subtype / genetics
Influenza A Virus, H1N1 Subtype / isolation & purification
Influenza A Virus, H1N1 Subtype / physiology*
Influenza, Human / diagnosis
Influenza, Human / drug therapy
Influenza, Human / virology
Kinetics
Male
Nasopharynx / virology*
Oseltamivir / therapeutic use*
Swine
Virus Shedding*

Substances

Antiviral Agents
Oseltamivir