Histone modifications do not play a major role in salicylate-mediated suppression of jasmonate-induced PDF1.2 gene expression

Commun Integr Biol. 2008;1(2):143-5. doi: 10.4161/cib.1.2.6997.

Abstract

Cross-talk between salicylic acid (SA) and jasmonic acid (JA) defense signaling pathways allows a plant to finely tune its response to the attacker encountered. In Arabidopsis, pharmacological experiments revealed that SA exerts a strong antagonistic effect on JA-responsive genes, such as PDF1.2, indicating that the SA pathway can be prioritized over the JA pathway. We investigated the putative role of histone modifications in the regulation of SA-mediated suppression of PDF1.2 transcription. Chromatin immunoprecipitation analysis using an antibody directed against acetylated histone H3 revealed that SA does not affect the association of this histone modification at the PDF1.2 promoter, suggesting that chromatin remodeling does not play a major role in SA/JA cross-talk.

Keywords: Arabidopsis; chromatin remodeling; cross-talk; jasmonic acid; plant immune response; salicylic acid.