Prevalence of neuroleptic-induced dystonia in mania and schizophrenia

Am J Psychiatry. 1990 Sep;147(9):1231-3. doi: 10.1176/ajp.147.9.1231.

Abstract

In a prospective study of 41 acutely psychotic patients, neuroleptic-induced dystonic reactions occurred in 62.5% of the manic patients (10 of 16) and 66.7% of the schizophrenic patients (10 of 15), a nonsignificant difference. These findings contradict a recent report suggesting a higher risk for this side effect in mania.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Adult
  • Antipsychotic Agents / adverse effects*
  • Bipolar Disorder / drug therapy*
  • Bipolar Disorder / psychology
  • Dose-Response Relationship, Drug
  • Drug Therapy, Combination
  • Dystonia / chemically induced*
  • Dystonia / epidemiology
  • Female
  • Haloperidol / adverse effects
  • Humans
  • Lithium / therapeutic use
  • Male
  • Prevalence
  • Prospective Studies
  • Schizophrenia / drug therapy*
  • Schizophrenia, Paranoid / drug therapy
  • Schizophrenia, Paranoid / psychology
  • Schizophrenic Psychology

Substances

  • Antipsychotic Agents
  • Lithium
  • Haloperidol