Prevalence of the set-1B and astA genes encoding enterotoxins in uropathogenic Escherichia coli clinical isolates

S M Soto; E Guiral; J Bosch; J Vila

doi:10.1016/j.micpath.2009.09.007

Prevalence of the set-1B and astA genes encoding enterotoxins in uropathogenic Escherichia coli clinical isolates

Microb Pathog. 2009 Dec;47(6):305-7. doi: 10.1016/j.micpath.2009.09.007. Epub 2009 Sep 13.

Authors

S M Soto¹, E Guiral, J Bosch, J Vila

Affiliation

¹ Microbiology Department, Hospital Clinic, IDIBAPS, University of Barcelona, Spain. sarasotog@yahoo.es

PMID: 19755142
DOI: 10.1016/j.micpath.2009.09.007

Abstract

One hundred seventy human uropathogenic Escherichia coli (UPEC) clinical isolates were compared with 35 E. coli strains isolated from feces of a control group to determine the presence of the set1, sen and astA genes encoding the ShET-1, ShET-2, and EAST toxins, respectively. Overall, 27 (16%), 8 (8%) and 0 UPEC isolates presented the set1B, the astA, and the sen genes, respectively. This is the first time the set gene has been found in UPEC clinical isolates.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacterial Toxins / genetics*
Bacterial Toxins / metabolism
Enterotoxins / genetics*
Enterotoxins / metabolism
Escherichia coli Infections / microbiology
Escherichia coli Proteins / genetics
Escherichia coli Proteins / metabolism
Gene Expression Regulation, Bacterial / physiology*
Humans
Shiga Toxins / genetics*
Shiga Toxins / metabolism
Urinary Tract Infections / microbiology
Uropathogenic Escherichia coli / genetics*
Uropathogenic Escherichia coli / metabolism*

Substances

Bacterial Toxins
Enterotoxins
Escherichia coli Proteins
Shiga Toxins
heat stable toxin (E coli)
senA protein, E coli