Metabolic syndrome and its components after liver transplantation: incidence, prevalence, risk factors, and implications

Clin Nutr. 2010 Apr;29(2):175-9. doi: 10.1016/j.clnu.2009.08.008. Epub 2009 Sep 23.

Abstract

Metabolic syndrome is defined as the mutual existence of obesity, impaired fasting glucose levels, insulin resistance, hypertension, and dyslipidemia. After liver transplantation, patients typically develop these disorders, and even though there has been minimal research focused on the chronic impact of this syndrome on post-liver transplant patients, studies point to an association with major vascular events and fibrosis. The aim of the current work is to review data on the incidence, prevalence, risk factors, and implications of metabolic syndrome and its components in patients who have undergone liver transplantation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Diabetes Mellitus / epidemiology
  • Diabetes Mellitus / etiology
  • Diabetes Mellitus / prevention & control
  • Dyslipidemias / epidemiology
  • Dyslipidemias / etiology
  • Dyslipidemias / prevention & control
  • Female
  • Humans
  • Hypertension / epidemiology
  • Hypertension / etiology
  • Hypertension / prevention & control
  • Immunosuppressive Agents / adverse effects
  • Incidence
  • Insulin Resistance / physiology
  • Liver Transplantation / adverse effects*
  • Male
  • Metabolic Syndrome / diagnosis
  • Metabolic Syndrome / epidemiology*
  • Metabolic Syndrome / physiopathology*
  • Metabolic Syndrome / prevention & control
  • Obesity / epidemiology
  • Obesity / etiology
  • Obesity / prevention & control
  • Prevalence
  • Risk Factors

Substances

  • Immunosuppressive Agents