The human Y chromosome shows a low level of DNA polymorphism

Ann Hum Genet. 1990 Oct;54(4):297-305. doi: 10.1111/j.1469-1809.1990.tb00385.x.

Abstract

Six new Y-specific probes have been isolated and are reported. Along with another six already described they have been used in a systemic search for male specific RFLPs. An overall number of 46515 nucleotides have been screened with 12 enzymes and no polymorphic pattern observed. Our data reveal a greatly reduced level of polymorphism compared with other chromosomes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromosome Banding
  • DNA Probes*
  • Female
  • Humans
  • Hybrid Cells
  • Male
  • Mice
  • Polymorphism, Restriction Fragment Length*
  • Restriction Mapping
  • Y Chromosome*

Substances

  • DNA Probes