Direct chemoselective synthesis of glyconanoparticles from unprotected reducing glycans and glycopeptide aldehydes

Chem Commun (Camb). 2009 Nov 14:(42):6367-9. doi: 10.1039/b911676a. Epub 2009 Oct 1.

Abstract

Chemoselective oxime coupling was used for facile conjugation of unprotected, reducing glycans and glycopeptide aldehydes with core?shell gold nanoparticles carrying reactive aminooxy groups on the organic shell.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemistry*
  • Glycopeptides / chemical synthesis
  • Glycopeptides / chemistry*
  • Gold / chemistry*
  • Metal Nanoparticles / chemistry*
  • Oximes / chemistry
  • Polysaccharides / chemical synthesis
  • Polysaccharides / chemistry*

Substances

  • Aldehydes
  • Glycopeptides
  • Oximes
  • Polysaccharides
  • Gold