Objective: To investigate the efficacy of tadalafil on nocturnal penile tumescence (NPT).
Methods: Thirty-four patients with organic erectile dysfunction (ED) were treated with oral tadalafil at the dose of 10 mg/3 d before bedtime. A month later, 14 of the patients were observed for NPT by nocturnal electrobioimpedance volumetric assessment (NEVA).
Results: The parameters of erectile function significantly improved in the 14 patients (P < 0.05).
Conclusion: Oral administration of minute dose of tadalafil can improve NPT in organic ED patients.