Specific recognition of lectins by oligonucleotide glycoconjugates and sorting on a DNA microarray

Chem Commun (Camb). 2009 Nov 28:(44):6795-7. doi: 10.1039/b915132j. Epub 2009 Sep 30.

Abstract

Two glycoconjugates bearing different DNA tags are mixed in solution with lectins; both interact with their specific lectin and the resulting complexes are sorted, according to their DNA sequences, at the surface of micro-reactors bearing the immobilised complementary DNA sequences.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Glycoconjugates / chemistry*
  • Lectins / isolation & purification*
  • Methods
  • Oligonucleotide Array Sequence Analysis / methods*
  • Oligonucleotides / chemistry*
  • Solutions

Substances

  • Glycoconjugates
  • Lectins
  • Oligonucleotides
  • Solutions