Deprotonation of the Asp1-Ala2 peptide bond induces modification of the dynamic copper(II) environment in the amyloid-beta peptide near physiological pH

Angew Chem Int Ed Engl. 2009;48(50):9522-5. doi: 10.1002/anie.200904512.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alanine
  • Alzheimer Disease
  • Amyloid beta-Peptides / chemistry*
  • Aspartic Acid
  • Binding Sites
  • Copper / chemistry*
  • Dipeptides / chemistry*
  • Humans
  • Hydrogen-Ion Concentration
  • Magnetic Resonance Spectroscopy

Substances

  • Amyloid beta-Peptides
  • Dipeptides
  • Aspartic Acid
  • Copper
  • Alanine