Abstract
How cells generate a single axis of polarity for mating, division, and movement is unknown. In this issue, Howell et al. (2009) use a synthetic biology approach to demonstrate that rapid competition for a soluble signaling component (Bem1) is essential to ensure a unique axis of polarity in budding yeast.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Comment
MeSH terms
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Adaptor Proteins, Signal Transducing / metabolism
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Cell Polarity*
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Saccharomyces cerevisiae / cytology*
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Saccharomyces cerevisiae / physiology
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Saccharomyces cerevisiae Proteins / metabolism
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cdc42 GTP-Binding Protein, Saccharomyces cerevisiae / metabolism
Substances
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Adaptor Proteins, Signal Transducing
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Saccharomyces cerevisiae Proteins
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BEM1 protein, S cerevisiae
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cdc42 GTP-Binding Protein, Saccharomyces cerevisiae