The prevalence of osteoporosis in patients with severe hip and knee osteoarthritis awaiting joint arthroplasty

Age Ageing. 2010 Mar;39(2):234-9. doi: 10.1093/ageing/afp222. Epub 2009 Dec 23.

Abstract

Background: the presence of osteoporosis in patients with hip and knee osteoarthritis (OA) has important implications for understanding disease progression and providing optimal surgical and medical management.

Objective: to determine the prevalence of osteoporosis among patients with osteoarthritis awaiting total knee arthroplasty or total hip arthroplasty aged between 65 and 80 years.

Design: cross-sectional observational study.

Setting: tertiary referral centre in Newcastle upon Tyne, UK.

Subjects: patients with osteoarthritis awaiting total knee hip arthroplasty aged between 65 and 80 years.

Methods: lumbar spine, bilateral femoral and forearm bone mineral density (BMD) measurements were obtained using dual-energy X-ray absorptiometry.

Results: the cohort consisted of 199 patients with a mean age of 72 years (SD 4), and 113 (57%) were women. The overall rate of osteoporosis at any site was 23% (46/199) and a further 43% (85/199) of patients would have been classified as osteopaenic according to World Health Organization criteria. Osteoporosis was more commonly detected in the forearm (14%) than the lumbar spine (8.5%) and proximal femur of the index side (8.2%).

Conclusions: in summary, a significant proportion of patients with end-stage OA have osteoporosis but this diagnosis may be missed unless BMD measurements are performed at sites distant from joints affected by OA.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorptiometry, Photon / methods
  • Aged
  • Aged, 80 and over
  • Bone Density / physiology*
  • Cross-Sectional Studies
  • Female
  • Femur / physiology
  • Forearm / physiology
  • Humans
  • Logistic Models
  • Male
  • Osteoarthritis, Hip / complications*
  • Osteoarthritis, Hip / diagnostic imaging
  • Osteoarthritis, Knee / complications*
  • Osteoarthritis, Knee / diagnostic imaging
  • Osteoporosis / complications
  • Osteoporosis / epidemiology*
  • Prevalence
  • Sex Factors
  • Spine / physiology
  • Surveys and Questionnaires
  • United Kingdom / epidemiology