Post-weaning effects of milk and milk components on the intestinal mucosa in inflammation

Mutat Res. 2010 Aug 7;690(1-2):64-70. doi: 10.1016/j.mrfmmm.2009.12.006. Epub 2009 Dec 29.

Abstract

Many milk-derived components have immunomodulatory and anti-inflammatory properties, and some of these reduce intestinal inflammation when orally administered to animal models of colitis. However, the potential for ruminant milk or milk components to benefit people with intestinal inflammatory disorders (such as Inflammatory Bowel Disease) has not been well-researched. This review describes published research into mechanisms by which ruminant milk and its components may have beneficial effects when consumed by people who have intestinal inflammation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / pharmacology
  • Humans
  • Inflammation / prevention & control*
  • Inflammatory Bowel Diseases / diet therapy
  • Inflammatory Bowel Diseases / prevention & control*
  • Intestinal Mucosa / drug effects
  • Intestinal Mucosa / immunology*
  • Intestinal Mucosa / physiology
  • Intestines
  • Milk / chemistry
  • Milk / physiology*
  • Milk Proteins / metabolism
  • Ruminants
  • Weaning

Substances

  • Anti-Inflammatory Agents
  • Milk Proteins