Abstract
A major challenge in bacterial pathogenesis is understanding the molecular basis of the switch from saprophytism to virulence. Following a recent whole-genome transcriptomic analysis using tiling arrays, an article published in BMC Genomics reports the first use of RNA-seq in Listeria monocytogenes in order to identify genes controlled by sigma B, a transcriptional regulator with a critical role in virulence.
MeSH terms
-
Antibodies, Bacterial
-
Base Sequence
-
Gene Expression Profiling*
-
Gene Expression Regulation, Bacterial
-
Listeria monocytogenes / genetics
-
Listeria monocytogenes / metabolism
-
Listeria monocytogenes / pathogenicity
-
Listeriosis / genetics
-
Listeriosis / physiopathology*
-
Oligonucleotide Array Sequence Analysis
-
Virulence / genetics*
-
Virulence Factors / genetics*
-
Virulence Factors / immunology
Substances
-
Antibodies, Bacterial
-
Virulence Factors