Determinant factors of fertility outcomes after laparoscopic colorectal resection for endometriosis

Eur J Obstet Gynecol Reprod Biol. 2010 Apr;149(2):210-4. doi: 10.1016/j.ejogrb.2009.12.032. Epub 2010 Jan 21.

Abstract

Objective: The aims of this prospective study were to evaluate fertility, pregnancy outcomes and their determinant factors after laparoscopic segmental colorectal resection for endometriosis.

Study design: We studied 83 women who underwent colorectal resection for endometriosis. Thirty-nine women (47%) had an associated infertility and 51 (61.4%) wished to conceive after surgery. Surgical route was exclusive laparoscopy in 77 cases (92.7%) and laparoconversion in 6 (7.3%).

Results: Twenty-nine pregnancies were obtained in 24 patients (43.6%) including 20 spontaneous (69%) and 9 by IVF (31%). The median time to conceive spontaneously was 6 months and 20 months by IVF. Among the 39 infertile women, 18 (46%) conceived during the study period. A relation was found between pregnancy rate and patient age (p=0.02). Reduction in pregnancy rate was correlated to the presence of adenomyosis (p=0.04) and high ASRM total score (p<0.001) as well as exclusive laparoscopy compared to conversion to laparotomy for colorectal resection (p=0.01).

Conclusion: Adenomyosis and conversion to laparotomy as well as patient age, ASRM score appeared determinant factors of fertility outcome.

MeSH terms

  • Adult
  • Age Factors
  • Colon / surgery
  • Endometriosis / surgery*
  • Female
  • Fertility*
  • Fertilization in Vitro
  • Humans
  • Infertility, Female / surgery
  • Laparoscopy*
  • Pregnancy
  • Pregnancy Outcome
  • Pregnancy Rate
  • Prospective Studies
  • Rectum / surgery