Midbrain and spinal cord magnetic resonance imaging (MRI) changes in poliomyelitis

J Child Neurol. 2010 Apr;25(4):497-9. doi: 10.1177/0883073809340918. Epub 2010 Feb 5.

Abstract

Poliomyelitis, though eradicated from most parts of the world, continues to occur in India. There is paucity of data on the magnetic resonance imaging (MRI) changes in poliomyelitis. We report a 3(1/2)-year-old boy who presented with subacute onset flaccid paralysis and altered sensorium. Stool culture was positive for wild polio virus type 3. Magnetic resonance imaging revealed signal changes in bilateral substantia nigra and anterior horns of the spinal cord. These MRI changes may be of potential diagnostic significance in a child with poliomyelitis.

Publication types

  • Case Reports

MeSH terms

  • Anterior Horn Cells / pathology
  • Anterior Horn Cells / virology
  • Child, Preschool
  • Comorbidity
  • Consciousness Disorders / pathology
  • Consciousness Disorders / physiopathology
  • Consciousness Disorders / virology
  • Fever / virology
  • Humans
  • India
  • Magnetic Resonance Imaging / methods*
  • Male
  • Mesencephalon / pathology*
  • Mesencephalon / physiopathology
  • Mesencephalon / virology
  • Muscular Atrophy / pathology
  • Muscular Atrophy / physiopathology
  • Muscular Atrophy / virology
  • Paralysis / physiopathology
  • Paralysis / virology
  • Parkinson Disease / pathology
  • Parkinson Disease / physiopathology
  • Parkinson Disease / virology
  • Poliomyelitis / pathology*
  • Poliomyelitis / physiopathology
  • Poliovirus Vaccine, Inactivated
  • Spinal Cord / pathology*
  • Spinal Cord / physiopathology
  • Spinal Cord / virology
  • Substantia Nigra / pathology
  • Substantia Nigra / virology
  • Time

Substances

  • Poliovirus Vaccine, Inactivated