Novel hot spot of IS6110 insertion in Mycobacterium tuberculosis

J Clin Microbiol. 2010 Apr;48(4):1422-4. doi: 10.1128/JCM.02210-09. Epub 2010 Feb 10.

Abstract

We describe a hot spot for the insertion of IS6110 in Mycobacterium tuberculosis located in the area of region of difference 724 (RD724). Because RD724 defines sublineage 724 of M. tuberculosis, caution must be exercised when screening for RD724, as different polymorphisms can be observed in this region.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • DNA Transposable Elements*
  • DNA, Bacterial / genetics*
  • Humans
  • Mutagenesis, Insertional*
  • Mycobacterium tuberculosis / genetics*
  • Polymorphism, Genetic*

Substances

  • DNA Transposable Elements
  • DNA, Bacterial