Hemangiopericytoma: collision with meningioma and recurrence

Neurol Sci. 2010 Oct;31(5):625-30. doi: 10.1007/s10072-010-0227-3. Epub 2010 Mar 3.

Abstract

Intracranial hemangiopericytomas are a rare type of primary brain tumor, representing only about 0.5% of all primary brain tumors. Even more rare is the co-existence of two juxtaposed primary brain tumors, termed a "collision" tumor. This report provides the first documentation in the literature of a hemangiopericytoma colliding with a meningioma, and recurring after treatment with gross total resection. Surgical samples were fully evaluated with hematoxylin and eosin and reticulin staining, as well as immunohistochemical analysis. Results were classically representative of a hemangiopericytoma (World Health Organization grade II) and of a meningioma (World Health Organization grade I). This report of a unique collision tumor not only augments the repertoire of collision tumor combinations described in literature but also provides follow-up on the clinical outcome of the patient, thereby raising clinically relevant issues ranging from presentation to treatment paradigms.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antigens, CD34 / metabolism
  • Brain Neoplasms / complications*
  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / metabolism
  • Hemangiopericytoma / complications*
  • Hemangiopericytoma / diagnosis
  • Hemangiopericytoma / metabolism
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Meningeal Neoplasms / complications*
  • Meningeal Neoplasms / diagnosis
  • Meningeal Neoplasms / metabolism
  • Meningioma / complications*
  • Meningioma / diagnosis
  • Meningioma / metabolism
  • Neoplasm Recurrence, Local / complications*
  • Neoplasm Recurrence, Local / metabolism
  • Recurrence

Substances

  • Antigens, CD34