Hypervirulent Clostridium difficile strains in hospitalized patients, Canada

Emerg Infect Dis. 2010 Apr;16(4):678-81. doi: 10.3201/eid1604.091152.

Abstract

To determine the incidence rate of infections with North American pulsed-field types 7 and 8 (NAP7/NAP8) strains of Clostrodium difficile, ribotype 078, and toxinotype V strains, we examined data collected for the Canadian Nosocomial Infections Surveillance Program (CNISP) CDI surveillance project during 2004-2008. Incidence of human infections increased from 0.5% in 2004/2005 to 1.6% in 2008.

MeSH terms

  • Aged
  • Canada / epidemiology
  • Clostridioides difficile / genetics
  • Clostridioides difficile / pathogenicity*
  • Cross Infection / epidemiology
  • Cross Infection / microbiology*
  • Electrophoresis, Gel, Pulsed-Field
  • Enterocolitis, Pseudomembranous / epidemiology
  • Enterocolitis, Pseudomembranous / microbiology*
  • Female
  • Genes, Bacterial / genetics
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Population Surveillance
  • Ribotyping
  • Sequence Analysis, DNA

Associated data

  • GENBANK/AM180355