[Use and abuse of drugs in cognitive impairment patients]

Vertex. 2010 Jan-Feb;21(89):18-23.
[Article in Spanish]

Abstract

Introduction: Irrational use of drugs for the treatment of cognitive impairment can increase health costs in developing countries.

Objective: to analyze the pattern of drug prescription related to the treatment of patients with dementia and to compare them with the income of patients.

Patients: 313 community-based outpatients that seeked medical advice for memory problems, in the Memory Center of Zubizarreta General Hospital (Buenos Aires, Argentina), were prospectively assessed during a period of a year.

Results: Patients' mean income was 502.81 "Pesos Argentinos" which is equivalent to US$152 per month (2007). Fourty one point fifty five percent (41.55%) of the patients had dementia, 15.65% psychiatric diseases, 15.01% mild cognitive impairment and 27.79% were normal. Patients received an average of 2.84 drugs/day, 20% of the patients took at least one drug for cognitive impairment (9.85% memantine, 6.38% donepezil and 4% nootropics, cerebral vasodilators or antioxidants), and 39.3% received psychotropic medication (28.11% benzodiazepines and 9.26 % atypical antipsychotics). Twelve point seventy six percent (12.76%) of the patients with mild cognitive impairment were treated with antidementials, 5.74% of normal subjects received antidementials. 4% of patients were exclusively treated with free samples.

Conclusion: In our sample irrational degree of using antidemential drugs and psychotropic agents was found.

Publication types

  • Comparative Study
  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cognition Disorders / drug therapy*
  • Cognition Disorders / economics*
  • Cross-Sectional Studies
  • Dementia / drug therapy*
  • Dementia / economics*
  • Drug Utilization / statistics & numerical data
  • Female
  • Humans
  • Income*
  • Male
  • Middle Aged
  • Prospective Studies