Lung adenocarcinoma, mixed subtype: histopathologic basis for high-resolution computed tomography findings

J Thorac Imaging. 2011 Feb;26(1):74-81. doi: 10.1097/RTI.0b013e3181c65a51.

Abstract

"Adenocarcinoma, mixed subtype" is the most common histologic subtype of lung adenocarcinomas in the World Health Organization classification of 2004. For small peripheral adenocarcinomas, for example, those measuring 2 cm or less in greatest diameter, invasive areas can present various histologic patterns. The purpose of this study is to present the radiologic features of small peripheral lung adenocarcinomas with or without a bronchioloalveolar component and with or without invasive areas, in comparison with histopathologic findings. For this purpose, a detailed evaluation of the characteristics of solid regions in ground-glass opacity on high-resolution computerized tomographic images of lung adenocarcinoma is useful.

MeSH terms

  • Adenocarcinoma of Lung
  • Adenocarcinoma* / diagnostic imaging
  • Adenocarcinoma* / pathology
  • Female
  • Humans
  • Lung Neoplasms* / diagnostic imaging
  • Lung Neoplasms* / pathology
  • Middle Aged
  • Tomography, X-Ray Computed*
  • World Health Organization