Translocation t(8;16)(p11;p13) in neonatal acute monocytic leukaemia

T Hanada; I Ono; Y Minosaki; N Moriyama; S Nakahara; A Ohtsu

doi:10.1007/BF01955931

Translocation t(8;16)(p11;p13) in neonatal acute monocytic leukaemia

Eur J Pediatr. 1991 Mar;150(5):323-4. doi: 10.1007/BF01955931.

Authors

T Hanada¹, I Ono, Y Minosaki, N Moriyama, S Nakahara, A Ohtsu

Affiliation

¹ Department of Paediatrics, University of Tsukuba, Ibaraki-ken, Japan.

PMID: 2044602
DOI: 10.1007/BF01955931

Abstract

A recent report demonstrated that t(8;16) (p11;p13) may be linked to acute monocytic leukaemia (AMoL) of differentiated subtype (M5b) with active haemophagocytosis by leukaemic cells. Only two cases of neonatal AMoL with t(8;16) (p11;p13) have been reported; M5b with haemophogocytosis and M5a. We report a case of neonatal AMoL (M5b) with t(8;16)(p11;p13), but haemophagocytosis by the leukaemic cells was not detected.

Publication types

Case Reports

MeSH terms

Chromosomes, Human, Pair 16*
Chromosomes, Human, Pair 8*
Humans
Infant, Newborn
Leukemia, Monocytic, Acute / genetics*
Leukemia, Monocytic, Acute / physiopathology
Phagocytosis / physiology
Translocation, Genetic / genetics*