Laparoscopic cholecystocholangiography for diagnosis of prolonged jaundice in infants, experience of 144 cases

Pediatr Surg Int. 2010 Jul;26(7):711-5. doi: 10.1007/s00383-010-2598-1. Epub 2010 May 12.

Abstract

Purpose: Cholangiography is often crucial for establishing the definitive diagnosis in infants with prolonged jaundice. Here, we describe our protocol of using the two-hole laparoscopic technique and discuss its benefits.

Methods: 144 consecutive patients with suspected biliary atresia were included in this retrospective study. A 5-mm umbilical port is introduced for a 30 degrees laparoscope. An additional 5-mm trocar was inserted at right subcostal incision. A liver biopsy was performed first if needed. The fundus of gallbladder was then exteriorized through the incision of the working port after pneumoperitoneum was released and a catheter is inserted into the gallbladder for cholangiography.

Results: The average duration of operation was 34 min (range 20-55 min). Laparoscopic cholangiography failed in 21 cases (14.6%) where atrophic gallbladder was found and BA was confirmed by subsequent laparotomy. For the remaining 123 cases, biliary atresia were diagnosed in 88 (71.5%), biliary hypoplasia in 14 (11.4%), and cholestasis in 21 (17.1%), respectively. There was no bleeding or any other complications intraoperatively.

Conclusion: The technique of laparoscopic cholecystocholangiography is simple, safe and efficient. It can provide an accurate diagnosis. Furthermore, for patients without biliary atresia, unnecessary laparotomy can be avoided.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biliary Atresia / complications
  • Biliary Atresia / diagnosis*
  • Cholangiography / methods*
  • Cholecystography / methods*
  • Female
  • Gallbladder / surgery
  • Gastric Fundus / surgery
  • Humans
  • Infant
  • Infant, Newborn
  • Jaundice / etiology*
  • Jaundice, Neonatal / etiology*
  • Laparoscopy / methods*
  • Male
  • Retrospective Studies
  • Sensitivity and Specificity
  • Treatment Outcome