Biophysics: Transporter in the spotlight

Nature. 2010 May 13;465(7295):171-2. doi: 10.1038/465171a.

Abstract

Membrane transporter proteins switch between conformational states to move substrates across membranes. The transition between these states can now be studied using single-molecule experiments.

Publication types

  • Comment
  • News

MeSH terms

  • Bacterial Proteins / chemistry*
  • Bacterial Proteins / metabolism*
  • Crystallography, X-Ray
  • Fluorescence Resonance Energy Transfer
  • Molecular Dynamics Simulation
  • Plasma Membrane Neurotransmitter Transport Proteins / chemistry*
  • Plasma Membrane Neurotransmitter Transport Proteins / metabolism*
  • Protein Conformation
  • Sodium / metabolism

Substances

  • Bacterial Proteins
  • Plasma Membrane Neurotransmitter Transport Proteins
  • Sodium