What is the role of somatic mutation in autosomal dominant polycystic kidney disease?

J Am Soc Nephrol. 2010 Jul;21(7):1073-6. doi: 10.1681/ASN.2010030328. Epub 2010 May 20.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Alleles
  • Animals
  • Cysts / genetics
  • Disease Models, Animal
  • Humans
  • Kidney Diseases / genetics
  • Mice
  • Mice, Knockout
  • Mutation / genetics*
  • Phenotype
  • Polycystic Kidney, Autosomal Dominant / genetics*
  • TRPP Cation Channels / genetics*

Substances

  • TRPP Cation Channels
  • polycystic kidney disease 1 protein
  • polycystic kidney disease 2 protein