Concomitant pulmonary infection with Nocardia transvalensis and Aspergillus ustus in lung transplantation

Miguel M Cabada; Shawn P Nishi; Alfred S Lea; Vicki Schnadig; Gisele A Lombard; Scott D Lick; Vincent G Valentine

doi:10.1016/j.healun.2010.04.016

Concomitant pulmonary infection with Nocardia transvalensis and Aspergillus ustus in lung transplantation

J Heart Lung Transplant. 2010 Aug;29(8):900-3. doi: 10.1016/j.healun.2010.04.016. Epub 2010 Jun 11.

Authors

Miguel M Cabada¹, Shawn P Nishi, Alfred S Lea, Vicki Schnadig, Gisele A Lombard, Scott D Lick, Vincent G Valentine

Affiliation

¹ Division of Infectious Diseases, University of Texas Medical Branch, Galveston, Texas 77555-0772, USA.

PMID: 20541440
DOI: 10.1016/j.healun.2010.04.016

Abstract

Lung infections with Nocardia and Aspergillus spp in lung transplant recipients (LTRs) create diagnostic and therapeutic challenges. The present case illustrates the difficulties in identifying these pathogens in LTRs. A high degree of clinical suspicion and aggressive early management are required to ensure good outcomes. Although prospective data on treating these conditions are scarce, the empiric use of combination broad-spectrum anti-microbials initially seems prudent.

Publication types

Case Reports

MeSH terms

Aged
Anti-Infective Agents / therapeutic use
Aspergillus*
Comorbidity
Humans
Idiopathic Pulmonary Fibrosis / immunology
Idiopathic Pulmonary Fibrosis / surgery*
Immunosuppression Therapy
Lung Diseases / diagnosis*
Lung Diseases / drug therapy
Lung Diseases / microbiology
Lung Transplantation* / immunology
Male
Nocardia Infections / diagnosis*
Nocardia Infections / drug therapy
Nocardia Infections / epidemiology
Nocardia*
Opportunistic Infections / diagnosis*
Opportunistic Infections / drug therapy
Opportunistic Infections / epidemiology
Pulmonary Aspergillosis / diagnosis*
Pulmonary Aspergillosis / drug therapy
Pulmonary Aspergillosis / epidemiology
Treatment Outcome

Substances

Anti-Infective Agents