1H, 15N and 13C assignments of an intramolecular Lmo2-LIM2/Ldb1-LID complex

Lorna E Wilkinson-White; Siavoush Dastmalchi; Ann H Kwan; Daniel P Ryan; Joel P Mackay; Jacqueline M Matthews

doi:10.1007/s12104-010-9240-y

1H, 15N and 13C assignments of an intramolecular Lmo2-LIM2/Ldb1-LID complex

Biomol NMR Assign. 2010 Oct;4(2):203-6. doi: 10.1007/s12104-010-9240-y. Epub 2010 Jun 19.

Authors

Lorna E Wilkinson-White¹, Siavoush Dastmalchi, Ann H Kwan, Daniel P Ryan, Joel P Mackay, Jacqueline M Matthews

Affiliation

¹ School of Molecular Bioscience, Building G08, University of Sydney, Sydney, NSW, 2006, Australia.

PMID: 20563763
DOI: 10.1007/s12104-010-9240-y

Abstract

Lmo2 is a LIM-only protein involved in hematopoiesis and the development of T-cell acute lymphoblastic leukaemia. Here we report backbone and side chain NMR assignments for an engineered intramolecular complex of the C-terminal LIM domain from Lmo2 tethered to the LIM interaction domain (LID) from LIM domain binding protein 1 (Ldb1).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Carbon Isotopes
DNA-Binding Proteins / chemistry*
DNA-Binding Proteins / metabolism*
Hydrogen
Molecular Sequence Data
Nitrogen Isotopes
Nuclear Magnetic Resonance, Biomolecular*
Protein Structure, Secondary
Protein Structure, Tertiary
Transcription Factors / chemistry*
Transcription Factors / metabolism*

Substances

Carbon Isotopes
DNA-Binding Proteins
Nitrogen Isotopes
Transcription Factors
Hydrogen