Benzodiazepine use among heroin users: baseline use, current use and clinical outcome

Drug Alcohol Rev. 2010 May;29(3):250-5. doi: 10.1111/j.1465-3362.2009.00101.x.

Abstract

Introduction and aims: Benzodiazepine use is associated with elevated levels of harm. The current study aimed to ascertain the long-term nature of the relationship between benzodiazepine use and clinical profile among heroin users.

Design and methods: Longitudinal cohort, with follow-up at 3, 12, 24 and 36 months. Participants were 615 heroin users recruited for the Australian Treatment Outcome Study.

Results: At baseline, current benzodiazepine users were more likely to be committing crime, had poorer psychological health and poorer physical health. Baseline benzodiazepine use was not associated with the likelihood across follow-up of heroin use (P = 0.44), committing crime (P = 0.17), poorer psychological health (P = 0.31) or poorer physical health (P = 0.48). Current benzodiazepine use was, however, associated with a greater likelihood of concurrent heroin use (OR 2.77), crime (OR 2.04), poorer psychological health (beta = -4.47) and poorer physical health (beta = -2.33).

Discussion and conclusions: Clinicians should be aware that reductions in benzodiazepine use are associated with reductions in harm, and that baseline benzodiazepine status does not equate to poor long-term outcome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Australia / epidemiology
  • Benzodiazepines / adverse effects*
  • Crime / statistics & numerical data
  • Female
  • Follow-Up Studies
  • Health Status
  • Heroin Dependence / complications
  • Heroin Dependence / epidemiology*
  • Humans
  • Male
  • Middle Aged
  • Risk Factors
  • Substance-Related Disorders / complications
  • Substance-Related Disorders / epidemiology*
  • Treatment Outcome

Substances

  • Benzodiazepines