Influence of smoking habits on the GA/HbA1c ratio in patients with type 1 diabetes mellitus

Med Princ Pract. 2010;19(5):415-7. doi: 10.1159/000316385. Epub 2010 Jul 14.

Abstract

Objective: To assess the influence of smoking on glycated albumin (GA) to hemoglobin A1c (HbA1c) ratio among type 1 diabetes mellitus (T1DM) patients.

Subjects and methods: Eighty-one T1DM patients (49 females, 32 males, mean age 48 +/- 18 years) were recruited, and data concerning GA/HbA1c ratio and smoking were collected.

Results: The median levels of GA and HbA1c were 23.3 and 7.4%, respectively. Independent of age, sex and/or body mass index, the GA/HbA1c ratio in smokers was significantly lower than that in nonsmokers (3.0 vs. 3.3, p < 0.05).

Conclusion: The data suggest that smoking might affect the GA/HbA1c ratio among T1DM patients.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Diabetes Mellitus, Type 1 / blood*
  • Female
  • Glycated Hemoglobin / metabolism*
  • Glycated Serum Albumin
  • Glycation End Products, Advanced
  • Humans
  • Male
  • Middle Aged
  • Serum Albumin / metabolism*
  • Smoking / blood*

Substances

  • Glycated Hemoglobin A
  • Glycation End Products, Advanced
  • Serum Albumin
  • Glycated Serum Albumin