Association between 2009 seasonal influenza vaccine and influenza-like illness during the 2009 pandemic: preliminary results of a large household transmission study in Western Australia

Euro Surveill. 2010 Jul 15;15(28):19616.

Abstract

We conducted a prospective household transmission study to examine whether receipt of 2009 trivalent influenza vaccine (TIV) was associated with increased risk of influenza-like illness (ILI) among contacts of confirmed pandemic influenza A(H1N1) 2009 patients. In the week following onset of pandemic illness in a household member, 46 (15%) of 304 TIV-vaccinated contacts, and 174 (15%) of 1,162 unvaccinated contacts developed ILI (p=0.95). Receipt of 2009 TIV had no effect on one's risk of pandemic illness.

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Child
  • Child, Preschool
  • Data Collection
  • Disease Outbreaks / prevention & control*
  • Family Characteristics*
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Infant, Newborn
  • Influenza A Virus, H1N1 Subtype / immunology*
  • Influenza Vaccines / administration & dosage*
  • Influenza, Human / epidemiology
  • Influenza, Human / prevention & control
  • Influenza, Human / transmission*
  • Male
  • Middle Aged
  • Prospective Studies
  • Risk Factors
  • Sex Distribution
  • Vaccination / statistics & numerical data
  • Western Australia / epidemiology
  • Young Adult

Substances

  • Influenza Vaccines