Complications related to access site after percutaneous coronary interventions: are the adverse events underreported?

Catheter Cardiovasc Interv. 2011 Apr 1;77(5):643-7. doi: 10.1002/ccd.22759. Epub 2011 Mar 8.

Abstract

Objectives: The primary objective was to compare the NCDR rate of four access site related complications (arteriovenous fistula, pseudoaneurysm, retroperitoneal bleed, and blood transfusion) with that obtained independently within a Quality Improvement (QI) Database. The secondary objective was to determine the in-hospital mortality related to these complications.

Background: NCDR is the most comprehensive database of post-PCI patients and a method by which hospitals are compared for quality of care and outcomes. The collected data include in-hospital events only, therefore reporting for same day and/or early discharges may fail to capture adverse events. We hypothesized that the actual rate of complications post-PCI may be higher than the rate reported in NCDR.

Methods: Adverse events following PCIs were collected in a QI database. We compared the rate of four above mentioned complications between NCDR and our QI database for the time period between January 1, 2005 and December 31, 2008.

Results: A total of 3,940 PCIs were performed on 3,430 patients in the four-year interval. The incidence of the combined endpoint of the four adverse events was 4.1% (161 events) in NCDR, vs. 4.7% (186 events) in QI database, a 13% higher yield. There was significantly higher in-hospital mortality in the complication group with regards to both all cause (4.7% vs. 1.1%, P < 0.0001) and cardiovascular mortality (2.7% vs. 1%, P = 0.046).

Conclusions: Access site related complications occurred 13% more than what was reported in NCDR and were associated with a greater than fourfold increase in in-hospital mortality.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aneurysm, False / etiology*
  • Aneurysm, False / mortality
  • Angioplasty, Balloon, Coronary / adverse effects*
  • Angioplasty, Balloon, Coronary / mortality
  • Arteriovenous Fistula / etiology*
  • Arteriovenous Fistula / mortality
  • Blood Transfusion* / mortality
  • Cardiac Catheterization / adverse effects*
  • Cardiac Catheterization / mortality
  • Chi-Square Distribution
  • Databases as Topic
  • Female
  • Hemorrhage / etiology*
  • Hemorrhage / mortality
  • Hospital Mortality
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Pennsylvania / epidemiology
  • Punctures
  • Quality Improvement
  • Quality Indicators, Health Care
  • Registries
  • Risk Assessment
  • Risk Factors
  • Time Factors