A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2 Å resolution

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Oct 1;66(Pt 10):1281-6. doi: 10.1107/S1744309110006548. Epub 2010 Jul 6.

Abstract

BT1062 from Bacteroides thetaiotaomicron is a homolog of Mfa2 (PGN0288 or PG0179), which is a component of the minor fimbriae in Porphyromonas gingivalis. The crystal structure of BT1062 revealed a conserved fold that is widely adopted by fimbrial components.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Bacteroides / chemistry*
  • Bacteroides / genetics
  • Crystallography, X-Ray
  • Fimbriae Proteins / chemistry*
  • Fimbriae Proteins / genetics
  • Fimbriae, Bacterial / chemistry*
  • Models, Molecular
  • Molecular Sequence Data
  • Protein Folding*
  • Protein Structure, Tertiary
  • Sequence Alignment
  • Structural Homology, Protein

Substances

  • Fimbriae Proteins

Associated data

  • PDB/3GF8