HDAC inhibitors induce cell cycle arrest, activate the apoptotic extrinsic pathway and synergize with a novel PIM inhibitor in Hodgkin lymphoma-derived cell lines

Br J Haematol. 2011 Feb;152(3):352-6. doi: 10.1111/j.1365-2141.2010.08401.x. Epub 2010 Oct 19.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / pharmacology*
  • Antineoplastic Combined Chemotherapy Protocols / pharmacology
  • Apoptosis / drug effects
  • Cell Cycle / drug effects
  • Drug Screening Assays, Antitumor
  • Drug Synergism
  • Histone Deacetylase Inhibitors / pharmacology*
  • Hodgkin Disease / pathology*
  • Humans
  • Proto-Oncogene Proteins c-pim-1 / antagonists & inhibitors
  • Tumor Cells, Cultured

Substances

  • Antineoplastic Agents
  • Histone Deacetylase Inhibitors
  • Proto-Oncogene Proteins c-pim-1
  • proto-oncogene proteins pim