A novel effect of adenovirus VA RNA1 on cytoplasmic mRNA abundance

C Svensson; G Akusjärvi

doi:10.1016/0042-6822(90)90116-9

A novel effect of adenovirus VA RNA1 on cytoplasmic mRNA abundance

Virology. 1990 Feb;174(2):613-7. doi: 10.1016/0042-6822(90)90116-9.

Authors

C Svensson¹, G Akusjärvi

Affiliation

¹ Department of Microbial Genetics, Karolinska Institutet, Stockholm, Sweden.

PMID: 2106186
DOI: 10.1016/0042-6822(90)90116-9

Abstract

Adenovirus VA RNA1 is a small RNA polymerase III transcript that enhances mRNA translation both in transfected cells and during a lytic virus infection. Here we present evidence that VA RNA1 also, in length-dependent manner, increases cytoplasmic mRNA abundance in transient expression assays in 293 cells.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adenoviridae / genetics*
Chloramphenicol O-Acetyltransferase / biosynthesis
Chloramphenicol O-Acetyltransferase / genetics
Cytoplasm / metabolism
DNA-Directed RNA Polymerases / physiology*
Protein Biosynthesis
RNA Polymerase III / physiology*
RNA, Messenger / analysis
RNA, Messenger / metabolism*
RNA, Viral / physiology*
Transfection
beta-Galactosidase / genetics

Substances

RNA, Messenger
RNA, Viral
Chloramphenicol O-Acetyltransferase
DNA-Directed RNA Polymerases
RNA Polymerase III
beta-Galactosidase