Dexmedetomidine: exploring its potential role and dosing guideline for its use in intractable pain in the palliative care setting

J Pain Palliat Care Pharmacother. 2010 Dec;24(4):384-6. doi: 10.3109/15360288.2010.518227.

Abstract

Intractable pain continues to pose problems for patients with life-limiting disease. The authors review the potential role of dexmedetomidine (Precedex), an α(2)-adrenergic agonist, as a bridge to obtaining effective analgesia. The authors offer criteria to consider in utilizing this medication within the context of palliative care.

MeSH terms

  • Analgesics, Non-Narcotic / administration & dosage
  • Analgesics, Non-Narcotic / therapeutic use*
  • Dexmedetomidine / administration & dosage
  • Dexmedetomidine / therapeutic use*
  • Humans
  • Pain, Intractable / drug therapy*
  • Palliative Care / methods
  • Practice Guidelines as Topic

Substances

  • Analgesics, Non-Narcotic
  • Dexmedetomidine