Malignant atrophic papulosis: a case report with severe visual and neurological impairment

Pediatr Dermatol. 2011 May-Jun;28(3):302-5. doi: 10.1111/j.1525-1470.2010.01287.x. Epub 2010 Dec 7.

Abstract

Malignant atrophic papulosis, or Degos' disease, is a severe systemic vasculopathy extremely rare in children. The skin, gastrointestinal tract, and central nervous system are most frequently affected. We report a 5-year-old girl with malignant atrophic papulosis who presented with widespread skin lesions from early infancy and severe visual and neurological impairment.

Publication types

  • Case Reports

MeSH terms

  • Brain Ischemia / etiology*
  • Child, Preschool
  • Female
  • Humans
  • Leukoencephalopathies / etiology*
  • Malignant Atrophic Papulosis / complications*
  • Malignant Atrophic Papulosis / pathology*
  • Severity of Illness Index
  • Skin / pathology
  • Vision Disorders / etiology*