Yushu of Qinghai Province is the mixed endemic area for cystic and alveolar hydatid diseases. Reviewing the previous data on the prevalence of the disease and the information from the communicable disease surveillance network during 2004 to April 15, 2010, possible impact of the Yushu earthquake was evaluated. It revealed that post-earthquake conditions might bring about risk factors for an increase of disease transmission, which included more deaths of livestock, increase of the number of stray dogs, poorer hygienic condition for local residents, etc. Countermeasures are proposed for preventing the spread of the disease in the disaster area.