Familial lung adenocarcinoma caused by the EGFR V843I germ-line mutation

J Clin Oncol. 2011 Mar 10;29(8):e191-2. doi: 10.1200/JCO.2010.31.4492. Epub 2010 Dec 20.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / genetics*
  • Adenocarcinoma / secondary
  • Adenocarcinoma / therapy
  • Adenocarcinoma, Papillary / genetics*
  • Adenocarcinoma, Papillary / therapy
  • Adult
  • Aged
  • Antineoplastic Agents / therapeutic use
  • Child
  • DNA Mutational Analysis
  • Drug Resistance, Neoplasm
  • ErbB Receptors / antagonists & inhibitors
  • ErbB Receptors / genetics*
  • Fatal Outcome
  • Female
  • Genetic Predisposition to Disease
  • Germ-Line Mutation*
  • Heredity
  • Humans
  • Lung Neoplasms / genetics*
  • Lung Neoplasms / pathology
  • Lung Neoplasms / therapy
  • Male
  • Middle Aged
  • Neoplasm Invasiveness
  • Neoplasm Staging
  • Pedigree
  • Phenotype
  • Pneumonectomy
  • Protein Kinase Inhibitors / therapeutic use
  • Treatment Failure

Substances

  • Antineoplastic Agents
  • Protein Kinase Inhibitors
  • EGFR protein, human
  • ErbB Receptors