Insulin resistance and the metabolic syndrome in obese children referred to an obesity center

J Pediatr Endocrinol Metab. 2010 Sep;23(9):943-51. doi: 10.1515/jpem.2010.151.

Abstract

Objective: The aim of this study was to describe insulin resistance and the metabolic syndrome in obese children and adolescents.

Subjects: The cohort consisted of 518 patients, 250 boys, 268 girls, age +/- sd: 11.8 +/- 3.2 years, BMIsds +/- sd: 2.94 +/- 0.5. A standard OGTT was performed.

Results: Impaired glucose tolerance was found in 9.4% of the boys and 5.5% of the girls. Impaired fasting glucose was found in 12.4% of the boys and 11.6% of the girls. The metabolic syndrome was present in 13.9% of children of 10 years or older. The proportion in which the metabolic syndrome was diagnosed was essentially not altered when pubertal groups were used instead of age groups.

Conclusion: Both impaired fasting glucose and impaired glucose tolerance as well as the metabolic syndrome are highly prevalent among obese children and adolescents.

MeSH terms

  • Adolescent
  • Age Factors
  • Child
  • Fasting / metabolism
  • Female
  • Glucose Intolerance
  • Humans
  • Insulin Resistance*
  • Male
  • Metabolic Syndrome / etiology*
  • Obesity / complications*
  • Referral and Consultation