Application of cycloaddition reactions to the syntheses of novel boron compounds

Molecules. 2010 Dec 21;15(12):9437-49. doi: 10.3390/molecules15129437.

Abstract

This review covers the application of cycloaddition reactions in forming the boron-containing compounds such as symmetric star-shaped boron-enriched dendritic molecules, nano-structured boron materials and aromatic boronic esters. The resulting boron compounds are potentially important reagents for both materials science and medical applications such as in boron neutron capture therapy (BNCT) in cancer treatment and as drug delivery agents and synthetic intermediates for carbon-carbon cross-coupling reactions. In addition, the use of boron cage compounds in a number of cycloaddition reactions to synthesize unique aromatic species will be reviewed briefly.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Boron / chemistry*
  • Boron Compounds / chemical synthesis*
  • Boron Compounds / chemistry*
  • Boron Neutron Capture Therapy / methods
  • Drug Delivery Systems
  • Humans
  • Neoplasms / drug therapy

Substances

  • Boron Compounds
  • Boron