A 73-year-old man admitted for anastomotic stricture not treated successfully with balloon dilation after proximal gastrectomy and fund plication in February 2009. Total gastrectomy and esophagojejunal anastomosis with mechanical stapler were performed. Dysphagia occurred after the operation and slack of jejunum mucosa directly under esophagojejunal anastomosis was observed with endoscope. Anastomotic stricture was not successfully treated with endoscopic balloon dilation. Therefore, APC was performed for slack of jejunum mucosa. As a result, anastomotic stricture was treated and had not reappeared until 1 year and 2 months later after APC. APC was safe and effective for anastomotic stricture of esophagojejunal anastomosis with mechanical stapler due to slack of jejunum mucosa.