Cross-link-governed dynamics of biopolymer networks

Phys Rev Lett. 2010 Dec 3;105(23):238101. doi: 10.1103/PhysRevLett.105.238101. Epub 2010 Nov 30.

Abstract

Recent experiments show that networks of stiff biopolymers cross-linked by transient linker proteins exhibit complex stress relaxation, enabling network flow at long times. We present a model for the dynamics controlled by cross-links in such networks. We show that a single microscopic time scale for cross-linker unbinding leads to a broad spectrum of macroscopic relaxation times and a shear modulus G ∼ ω(1/2) for low frequencies ω. This model quantitatively describes the measured rheology of actin networks cross-linked with α-actinin-4 over more than four decades in frequency.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Biopolymers / chemistry*
  • Computer Simulation
  • Cross-Linking Reagents / chemistry*
  • Models, Biological*
  • Rheology
  • Stress, Mechanical

Substances

  • Biopolymers
  • Cross-Linking Reagents