Osteomyelitis due to trimethoprim/sulfamethoxazole-resistant Edwardsiella tarda infection in a patient with X-linked chronic granulomatous disease

T Kawai; H Kusakabe; A Seki; S Kobayashi; M Onodera

doi:10.1007/s15010-011-0080-1

Osteomyelitis due to trimethoprim/sulfamethoxazole-resistant Edwardsiella tarda infection in a patient with X-linked chronic granulomatous disease

Infection. 2011 Apr;39(2):171-3. doi: 10.1007/s15010-011-0080-1. Epub 2011 Jan 19.

Authors

T Kawai¹, H Kusakabe, A Seki, S Kobayashi, M Onodera

Affiliation

¹ Department of Human Genetics, National Center for Child Health and Development, Tokyo, Japan. kawai-t@ncchd.go.jp

PMID: 21246245
DOI: 10.1007/s15010-011-0080-1

Abstract

Edwardsiella tarda, a catalase-positive bacillus widely distributed throughout nature, is generally susceptible to trimethoprim/sulfamethoxazole. We describe osteomyelitis due to trimethoprim/sulfamethoxazole-resistant E. tarda in a patient with chronic granulomatous disease (CGD). Once E. tarda acquires antibiotic resistance, infected CGD patients may develop severe infections with unforeseeable consequences.

Publication types

Case Reports

MeSH terms

Adolescent
Anti-Bacterial Agents / pharmacology*
Drug Resistance, Bacterial*
Edwardsiella tarda / drug effects
Edwardsiella tarda / isolation & purification*
Enterobacteriaceae Infections / diagnosis*
Enterobacteriaceae Infections / microbiology
Enterobacteriaceae Infections / pathology
Granulomatous Disease, Chronic / complications*
Humans
Infant, Newborn
Leg / diagnostic imaging
Leg / pathology
Magnetic Resonance Imaging
Male
Osteomyelitis / microbiology*
Osteomyelitis / pathology
Radiography
Trimethoprim, Sulfamethoxazole Drug Combination / pharmacology*

Substances

Anti-Bacterial Agents
Trimethoprim, Sulfamethoxazole Drug Combination