The role of the pyridoxine (vitamin B6) biosynthesis enzyme PDX1 in ultraviolet-B radiation responses in plants

Plant Physiol Biochem. 2011 Mar;49(3):284-92. doi: 10.1016/j.plaphy.2011.01.003. Epub 2011 Jan 12.

Abstract

Ultraviolet-B radiation regulates plant growth and morphology at low and ambient fluence rates but can severely impact on plants at higher doses. Some plant UV-B responses are related to the formation of reactive oxygen species (ROS) and pyridoxine (vitamin B(6)) has been reported to be a quencher of ROS. UV-B irradiation of Arabidopsis Col-0 plants resulted in increased levels of PDX1 protein, compared with UV-A-exposed plants. This was shown by immunoblot analysis using specific polyclonal antibodies raised against the recombinant PDX1.3 protein and confirmed by mass spectrometry analysis of immunoprecipitated PDX1. The protein was located mainly in the cytosol but also to a small extent in the membrane fraction of plant leaves. Immunohistochemical analysis performed in pea revealed that PDX1 is present in UV-B-exposed leaf mesophyll and palisade parenchyma but not in epidermal cells. Pyridoxine production increased in Col-0 plants exposed to 3 days of UV-B, whereas in an Arabidopsis pdx1.3 mutant UV-B did not induce pyridoxine biosynthesis. In gene expression studies performed after UV-B exposure, the pdx1.3 mutant showed elevated transcript levels for the LHCB1*3 gene (encoding a chlorophyll a/b-binding protein of the photosystem II light-harvesting antenna complex) and the pathogenesis-related protein 5 (PR-5) gene, compared with wild type.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptation, Physiological* / genetics
  • Arabidopsis / enzymology*
  • Arabidopsis / genetics
  • Arabidopsis / radiation effects
  • Arabidopsis Proteins / genetics
  • Arabidopsis Proteins / metabolism*
  • Carbon-Nitrogen Lyases
  • Cell Membrane / radiation effects
  • Cytosol / radiation effects
  • Gene Expression
  • Light-Harvesting Protein Complexes / genetics
  • Light-Harvesting Protein Complexes / metabolism
  • Mutation
  • Nitrogenous Group Transferases / genetics
  • Nitrogenous Group Transferases / metabolism*
  • Photosystem II Protein Complex / physiology
  • Photosystem II Protein Complex / radiation effects
  • Pisum sativum / enzymology*
  • Pisum sativum / radiation effects
  • Plant Leaves / metabolism
  • Plant Leaves / radiation effects
  • Plant Leaves / ultrastructure
  • Plant Proteins / genetics
  • Plant Proteins / metabolism
  • Pyridoxine / biosynthesis*
  • Recombinant Proteins / metabolism
  • Stress, Physiological* / genetics
  • Ultraviolet Rays*

Substances

  • Arabidopsis Proteins
  • Light-Harvesting Protein Complexes
  • Photosystem II Protein Complex
  • Plant Proteins
  • Recombinant Proteins
  • pathogenesis-related proteins, plant
  • Nitrogenous Group Transferases
  • Carbon-Nitrogen Lyases
  • At2g38230 protein, Arabidopsis
  • Pyridoxine