Nitric oxide enhances plant ultraviolet-B protection up-regulating gene expression of the phenylpropanoid biosynthetic pathway

Plant Cell Environ. 2011 Jun;34(6):909-921. doi: 10.1111/j.1365-3040.2011.02289.x. Epub 2011 Mar 24.

Abstract

The link between ultraviolet (UV)-B, nitric oxide (NO) and phenylpropanoid biosynthetic pathway (PPBP) was studied in maize and Arabidopsis. The transcription factor (TF) ZmP regulates PPBP in maize. A genetic approach using P-rr (ZmP+) and P-ww (ZmP⁻) maize lines demonstrate that: (1) NO protects P-rr leaves but not P-ww from UV-B-induced reactive oxygen species (ROS) and cell damage; (2) NO increases flavonoid and anthocyanin content and prevents chlorophyll loss in P-rr but not in P-ww and (3) the NO scavenger 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (cPTIO) blocks the UV-B-induced expression of ZmP and their targets CHS and CHI suggesting that NO plays a key role in the UV-B-regulated PPBP. Involvement of endogenous NO was studied in Arabidopsis nitric oxide dioxygenase (NOD) plants that express a NO dioxygenase gene under the control of a dexamethasone (DEX)-inducible promoter. Expression of HY5 and MYB12, TFs involved in PPBP regulation, was induced by UV-B, reduced by DEX in NOD plants and recovered by subsequent NO treatment. C4H regulates synapate esters synthesis and is UV-B-induced in a NO-independent pathway. Data indicate that UV-B perception increases NO concentration, which protects plant against UV-B by two ways: (1) scavenging ROS; and (2) up-regulating the expression of HY5, MYB12 and ZmP, resulting in the PPBP activation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis / drug effects
  • Arabidopsis / enzymology
  • Arabidopsis / genetics
  • Arabidopsis / radiation effects
  • Ascorbate Peroxidases
  • Biosynthetic Pathways / drug effects
  • Biosynthetic Pathways / genetics*
  • Biosynthetic Pathways / radiation effects
  • Catalase / metabolism
  • Gene Expression Regulation, Plant / drug effects*
  • Gene Expression Regulation, Plant / radiation effects
  • Nitric Oxide / metabolism
  • Nitric Oxide / pharmacology*
  • Oxygenases / metabolism
  • Peroxidases / metabolism
  • Phenols / metabolism*
  • Plant Leaves / drug effects
  • Plant Leaves / enzymology
  • Plant Leaves / radiation effects
  • Plant Proteins / genetics
  • Plant Proteins / metabolism
  • Ultraviolet Rays*
  • Up-Regulation / drug effects*
  • Up-Regulation / radiation effects
  • Zea mays / drug effects
  • Zea mays / genetics
  • Zea mays / radiation effects

Substances

  • Phenols
  • Plant Proteins
  • Nitric Oxide
  • Peroxidases
  • Ascorbate Peroxidases
  • Catalase
  • Oxygenases
  • nitric oxide dioxygenase