Severe intra-abdominal bleeding from neglected omental implantation of ectopic tissue after methotrexate treatment for persistent ectopic pregnancy

Fertil Steril. 2011 Jun;95(7):2435.e1-3. doi: 10.1016/j.fertnstert.2011.01.165. Epub 2011 Feb 19.

Abstract

Objective: To describe a case of severe intra-abdominal bleeding from omental implants after laparoscopic linear salpingostomy for ectopic pregnancy (EP).

Design: Case report.

Setting: A medical center.

Patient(s): A 27-year-old woman, presenting 15 days after methotrexate (MTX) treatment for persistent EP (35 days after laparoscopic linear salpingostomy for EP).

Intervention(s): Partial omentectomy.

Main outcome measure(s): Serial β-hCG levels after partial omentectomy.

Result(s): Histopathologic examination confirmed omental pregnancy. Her β-hCG levels decreased rapidly from 1,673 mIU/mL to 1.35 mIU/mL within 14 days after partial omentectomy.

Conclusion(s): Persistent EP after laparoscopic linear salpingostomy can occur in the omentum; meticulous clinical follow-up should be performed, especially when IM MTX injection was used as the salvage treatment for persistent EP.

Publication types

  • Case Reports

MeSH terms

  • Abortifacient Agents, Nonsteroidal / therapeutic use*
  • Abortion, Induced / methods*
  • Adult
  • Biomarkers / blood
  • Chorionic Gonadotropin, beta Subunit, Human / blood
  • Female
  • Hemorrhage / etiology*
  • Hemorrhage / surgery
  • Humans
  • Laparoscopy / adverse effects*
  • Methotrexate / therapeutic use*
  • Omentum
  • Pregnancy
  • Pregnancy, Ectopic / blood
  • Pregnancy, Ectopic / etiology
  • Pregnancy, Ectopic / therapy*
  • Pregnancy, Tubal / blood
  • Pregnancy, Tubal / therapy*
  • Reoperation
  • Salpingostomy / adverse effects*
  • Salpingostomy / methods
  • Salvage Therapy
  • Severity of Illness Index
  • Treatment Outcome

Substances

  • Abortifacient Agents, Nonsteroidal
  • Biomarkers
  • Chorionic Gonadotropin, beta Subunit, Human
  • Methotrexate