Clinical trial experience with transcatheter aortic valve insertion

Int J Cardiovasc Imaging. 2011 Dec;27(8):1143-54. doi: 10.1007/s10554-011-9825-2. Epub 2011 Feb 20.

Abstract

Surgical aortic valve replacement has long been considered the standard of care for patients with severe symptomatic aortic stenosis, however, an aging population with increasing complex comorbidities now represents a growing population of patients that is often considered inoperable for a traditional surgical approach. Transcatheter aortic valve implantation is a developing technology that offers an alternative treatment modality for these very high risk patients. This manuscript will review the currently available clinical trial data with transcatheter aortic valve implantation and offer perspective as to the future of this novel technology.

Publication types

  • Review

MeSH terms

  • Aortic Valve Stenosis / therapy*
  • Cardiac Catheterization* / adverse effects
  • Cardiac Catheterization* / instrumentation
  • Clinical Trials as Topic*
  • Evidence-Based Medicine
  • Heart Valve Prosthesis
  • Heart Valve Prosthesis Implantation / adverse effects
  • Heart Valve Prosthesis Implantation / instrumentation
  • Heart Valve Prosthesis Implantation / methods*
  • Humans
  • Prosthesis Design
  • Treatment Outcome